Indianapolis, Indiana

The city shattered expectations of Midwestern dining a couple of years ago with the opening of beloved brunch spot Milktooth, and the culinary scene has only gathered steam since then. In the fall, Indy hopped on the fried-chicken trend with Crispy Bird, a sustainability-focused joint from James Beard Award–nominated restaurateur Martha Hoover, while Milktooth’s Jonathan Brooks lent his expertise to the gastropub menu at the Owner’s Wife. This coming year, Sun King Brewery will open a 15,000-square-foot distillery in nearby Carmel. And with hotels in the works from 21c, Ironworks, and home-goods brand West Elm, Indianapolis is poised to become America’s next big destination. —Lila Battis